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IDEXX ALV Ag Test
Avian Leukosis Virus (ALV)
The IDEXX ALV Ag Test detects p27, an antigen common to all subgroups of ALV, including endogenous viruses. The recommended sample types are light albumin and cloacal swabs. While serum has been validated for use on the ALV antigen test, it is not a recommended sample for the detection of exogenous virus because of potential interference from endogenous sequences.
* Availability / Distribution: Worldwide
Test details
Features
- Albumin, cloacal swab and serum samples
- Antigen-capture format
Part numbers and sizes
99-09254 (5 plates/solid)
Avian Leukosis Virus (ALV)
Lymphoid leukosis, the most common manifestation of the avian leukosis/sarcoma group of viruses, produces a variety of neoplastic diseases, including erythroblastosis, myelocytomatosis, myeloblastosis and others. Not all infected birds will develop tumors. Infection can occur horizontally from bird to bird by direct or indirect contact, or vertically from an infected hen to her eggs as virus is shed into the albumin of the egg. In addition, vertical transmission may occur from virus incorporated in the DNA of a germ cell. Viremia in the hen is strongly associated with the transmission of virus congenitally. Enzyme immunoassays have proven efficacious in the detection of both leukosis antibody and antigen.
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* Not all products are available and/or registered in every country.
References:
- Payne LN, et al. A novel subgroup of exogenous avian leukosis virus in chickens. Journal of General Virolog. 1991;72:801–807.
- Payne LN, Fadly AM. Neoplastic diseases/Leukosis/Sarcoma group. In: Calnek BW, et al., eds. Diseases of Poultry. 10th ed. Ames, Ia: Iowa State University Press; 1997:414–466.
- Payne LN. HPRS-103: A retrovirus strikes back. The emergence of subgroup J avian leukosis virus. Avian Pathology. 1998;27:36–45.
- Payne LN, Gillespie AM, Howes K. Unsuitability of chicken sera for detection of exogenous ALV by the group-specific antigen ELISA. Veterinary Record. May 1993:555–557.